Differential effects of the intraventricular administration of 6-hydroxydopamine on the induction of type II ?-tubulin and tyrosine hydroxylase mRNA in the locus coeruleus of the aging Fischer 344 rat

1996 ◽  
Vol 364 (2) ◽  
pp. 363-381 ◽  
Author(s):  
James R. Unnerstall ◽  
Molly M. Long
Keyword(s):  
Tyrosine Hydroxylase ◽  
Locus Coeruleus ◽  
Intraventricular Administration ◽  
Type Ii ◽  
Differential Effects ◽  
Fischer 344 ◽  
Fischer 344 Rat ◽  
6 Hydroxydopamine

Long term effect of RU24722 on tyrosine hydroxylase in the rat locus coeruleus: differential effects of two enantiomeric forms

1993 ◽  
Vol 23 (6) ◽  
pp. 567-574 ◽  
Author(s):  
O. Bourde ◽  
P. Schmitt ◽  
F. Robert ◽  
F. Richard ◽  
A.-C. Carbonnele ◽  
...  
Keyword(s):  
Tyrosine Hydroxylase ◽  
Locus Coeruleus ◽  
Term Effect ◽  
Differential Effects ◽  
Long Term Effect

Influence of the Alpha2 Noradrenergic Antagonist Piperoxane on Longevity in the Fischer-344 Rat: A Preliminary Report

1995 ◽  
Vol 77 (1) ◽  
pp. 139-142 ◽  
Author(s):  
David M. Compton ◽  
Kerri L. Dietrich ◽  
Jeff S. Smith
Keyword(s):  
Locus Coeruleus ◽  
Preliminary Report ◽  
Aging Process ◽  
Fischer 344 Rats ◽  
Fischer 344 ◽  
Brain Levels ◽  
Fischer 344 Rat

Piperoxane is an α2-noradrenergic antagonist with demonstrated excitatory effects on neurons in the locus coeruleus, causing a corresponding increase in norepinephrine in many forebrain areas. 16 male Fischer-344 rats approximately 16 months of age were injected with 3 mg/kg of piperoxane or .09% saline. The piperoxane-treated rats lived an average of 127.1 days longer than the saline-treated rats. The results are discussed in terms of the effects of strategies designed to enhance brain levels of catecholamine and their effect on the aging process. A discussion of further research is also presented.

Antagonism by Progesterone of Diethylstilbestrol-lnduced Pituitary Tumorigenesis in Fischer 344 Rats: Effects on Sex Steroid Receptors and Tyrosine Hydroxylase mRNA

1996 ◽  
Vol 63 (6) ◽  
pp. 530-539 ◽  
Author(s):  
Gerardo G. Piroli ◽  
Claudia A. Grillo ◽  
Monica G. Ferrini ◽  
Victoria Lux-Lantos ◽  
Alejandro F. De Nicola
Keyword(s):  
Tyrosine Hydroxylase ◽  
Steroid Receptors ◽  
Sex Steroid ◽  
Fischer 344 Rats ◽  
Fischer 344 ◽  
Sex Steroid Receptors ◽  
Pituitary Tumorigenesis

Effects of a primary immune response to T-cell dependent antigen on serotonin metabolism in frontal cortex: in vivo microdialysis study in freely moving Fischer 344 rat

1994 ◽  
Vol 645 (1-2) ◽  
pp. 150-156 ◽  
Author(s):  
Alain M. Gardier ◽  
Sébastien Kachaner ◽  
Elisabeth Khan Shaghaghi ◽  
Christian Blot ◽  
Claude Bohuon ◽  
...  
Keyword(s):  
Immune Response ◽  
T Cell ◽  
In Vivo Microdialysis ◽  
Primary Immune Response ◽  
Serotonin Metabolism ◽  
Fischer 344 ◽  
Fischer 344 Rat ◽  
Freely Moving ◽  
Microdialysis Study
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